• The association between infant salivary cortisol and parental presence in the neonatal intensive care unit during and after COVID-19 visitation restrictions: A cross-sectional study 

      Brekke, Stine Marie; Halvorsen, Silje Torp; Bjørkvoll, Julie; Thorsby, Per Medbøe; Rønnestad, Arild Erland; Zykova, Svetlana; Bakke, Liv Hanne; Dahl, Sandra Rinne; Haaland, Kirsti; Siw Helen, Westby Eger; Solberg, Marianne Trygg; Solevåg, Anne Lee (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-07)
      Objectives: Parent-infant interaction in the neonatal intensive care unit (NICU) promotes health and reduces infant stress. During the COVID-19 pandemic, however, NICUs restricted parent-infant interaction to reduce viral transmission. This study examined the potential relationship between pandemic visitation restrictions, parental presence and infant stress as measured by salivary cortisol. Methods: ...
    • Combined hormonal contraceptives and vitamin D metabolism in adolescent girls 

      Öberg, Eva Gunnel Johanna; Jorde, Rolf; Figenschau, Professor Yngve; Thorsby, Per Medbøe; Dahl, Sandra Rinne; Winther, Anne; Grimnes, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-31)
      Objective: Combined hormonal contraceptive (CHC) use has been associated with higher total 25-hydroxyvitamin D (25(OH)D) levels. Here, we investigate the relation between CHC use and vitamin D metabolism to elucidate its clinical interpretation. <p>Methods: The cross-sectional Fit Futures 1 included 1038 adolescents. Here, a subgroup of 182 girls with available 25(OH)D, 1,25-dihydroxyvitamin D ...
    • Effects of vitamin D supplementation on bone turnover markers and other bone-related substances in subjects with vitamin D deficiency 

      Jorde, Rolf; Stunes, Astrid Kamilla; Kubiak, Julia Magdalena; Joakimsen, Ragnar Martin; Grimnes, Guri; Thorsby, Per Medbøe; Syversen, Unni (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-05)
      In observational studies, vitamin D deficiency is a risk factor for low bone density and future fractures, whereas a causal relation has been difficult to show in randomized controlled trials (RCTs). Similarly, vitamin D deficiency has been associated with increased bone turnover, but RCTs with vitamin D have not shown conclusive effects. This could be due to inclusion of vitamin D sufficient subjects ...
    • Effects of Vitamin D binding protein phenotypes and Vitamin D supplementation on serum total 25(OH)D and directly measured free 25(OH)D 

      Sollid, Stina Therese; Strand Hutchinson, Moira; Berg, Vivian; Fuskevåg, Ole-Martin; Figenschau, Yngve Anton; Thorsby, Per Medbøe; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-05)
      Objective:<br>To determine the relationship between serum total 25-hydroxyvitamin D (25(OH)D), directly measured free 25(OH)D and calculated free 25(OH)D with regard to vitamin D-binding protein (DBP) phenotypes, sex, BMI, age and season, and their interrelationship to vitamin D supplementation.<br>Design, patients and interventions:<br>A randomized controlled trial with 20 000 IU of vitamin D3 per ...
    • Plasma-Metanephrines in Patients with Autoimmune Addison’s Disease with and without Residual Adrenocortical Function 

      Åkerman, Anna-Karin; Sævik, Åse Bjorvatn; Thorsby, Per Medbøe; Methlie, Paal; Quinkler, Marcus; Jørgensen, Anders Palmstrøm; Höybye, Charlotte; Debowska, Aleksandra; Nedrebø, Bjørn Gunnar; Dahle, Anne Lise; Carlsen, Siri; Tomkowicz, Aneta; Sollid, Stina Therese; Nermoen, Ingrid; Grønning, Kaja; Dahlqvist, Per; Grimnes, Guri; Skov, Jakob; Finnes, Trine Elisabeth; Wahlberg, Jeanette; Holte, Synnøve Emblem; Simunkova, Katerina; Kämpe, Olle; Husebye, Eystein Sverre; Øksnes, Marianne; Bensing, Sophie (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-22)
      Purpose: Residual adrenocortical function, RAF, has recently been demonstrated in one-third of patients with autoimmune Addison’s disease (AAD). Here, we set out to explore any influence of RAF on the levels of plasma metanephrines and any changes following stimulation with cosyntropin. Methods: We included 50 patients with verified RAF and 20 patients without RAF who served as controls upon cosyntropin ...
    • Smoking and other determinants of bone turnover 

      Jorde, Rolf; Stunes, Astrid Kamilla; Kubiak, Julia Magdalena; Grimnes, Guri; Thorsby, Per Medbøe; Syversen, Unni (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-25)
      The balance between bone resorption and formation may be assessed by measurement of bone turnover markers (BTMs), like carboxyl-terminal cross-linked telopeptide of type 1 collagen (CTX-1) and procollagen type 1 amino-terminal propeptide (P1NP). Smoking has been shown to influence bone turnover and to reduce bone mass density (BMD), the exact mechanism for this is, however, not settled. In this ...
    • Stress responses to repeated captures in a wild ungulate 

      Trondrud, Liv Monica; Ugland, Cassandra Regine; Ropstad, Erik; Loe, Leif Egil; Albon, Steve; Stien, Audun; Evans, Alina; Thorsby, Per Medbøe; Veiberg, Vebjørn; Irvine, R. Justin; Pigeon, Gabriel (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-29)
      While capture-mark-recapture studies provide essential individual-level data in ecology, repeated captures and handling may impact animal welfare and cause scientific bias. Evaluating the consequences of invasive methodologies should be an integral part of any study involving capture of live animals. We investigated short- and long-term stress responses to repeated captures within a winter on the ...
    • Vitamin D supplementation does not improve CVD risk factors in vitamin D-insufficient subjects 

      Kubiak, Julia Magdalena; Thorsby, Per Medbøe; Kamycheva, Elena; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06)
      <p><i>Objective</i>: Low serum 25(OH)D levels are associated with cardiovascular disease (CVD) and some of its risk factors. However, in interventional studies, the effects of vitamin D supplementation have been uncertain, possibly due to inclusion of vitamin D-sufficient subjects. Our aim was therefore to examine effects of vitamin D supplementation on CVD risk factors in vitamin D-insufficient ...